Tachizaki, M., Sakamoto, S., Kobori, Y., Asano, Y., Kawaguchi, S., Seya, K., Tanaka, H., Morita, E. , Imaizumi, T. Interferon-stimulated gene 56 positively regulates Toll-like receptor 3-mediated CXCL10 expression in human renal proximal tubular epithelial cells. FEBS Open Bio. 2024 Aug;14(8):1303-1319. doi: 10.1002/2211-5463.13851.
Izumida, K., Morita, E. The roles of HCV core protein and its binding host factor in virus assembly and release. Frontiers in Virology 2024 4:1383261 doi:10.3389/fviro.2024.1383261
Konno, Y., Uriu, K., Chikata, T., Takada, T., Kurita, J.I., Ueda, M.T., Islam, S., Yang, Tan B.J., Ito, J., Aso, H., Kumata, R., Williamson, C., Iwami, S., Takiguchi, M., Nishimura, Y., Morita, E., Satou, Y., Nakagawa, S., Koyanagi, Y., Sato, K. Two-step evolution of HIV-1 budding system leading to pandemic in the human population. Cell Rep. 2024 43(2):113697. doi: 10.1016/j.celrep.2024.113697.
Izumida, K., Hara, Y., Furukawa, Y., Ishida, K., Tabata, K.,Morita, E. Purification of Hepatitis C Virus Core Protein in Non-Denaturing Condition. J Virol Methods. 2024 Jan; 322:114852 doi: 10.1016/j.jviromet.2023.114852.
Maeda, K., Goto, S., Miura, K., Saito, K., Morita, E. The Incorporation of Extracellular Vesicle Markers Varies Among Vesicles with Distinct Surface Charges. J Biochem. 2024 175(3):299-312 doi: 10.1093/jb/mvad097.
Ishida, K., Yagi, H., Kato, Y., Morita, E. N-linked glycosylation of flavivirus E protein contributes to viral particle formation. PLoS Pathog. 2023 19(10):e1011681. doi: 10.1371/journal.ppat.1011681.
Hashimoto, K., Kimura, K., Ishida, K., Morita, E. Tanaka, K., Hashimoto, M. HIV-1 Integrase Inhibitor, Dihydroobionin B, and the Investigation of its Extraordinary Specific Rotation. J Nat Prod. 2023 86(9): 2139-2144. 10.1021/acs.jnatprod.3c00353
Miura, K., Suzuki, Y., Ishida, K., Arakawa, M., Wu, H., Fujioka, Y., Emi, A., Maeda, K., Hamajima, R., Nakano, T., Tenno, T., Hiroaki, H., Morita, E. Distinct Motifs in the E Protein are Required for SARS-CoV-2 Virus Particle Formation and Lysosomal Deacidification in Host Cells. J Virol. 2023 e0042623. doi: 10.1128/jvi.00426-23.
Arakawa, M., Morita, E. Protein Pull-down Assay Using HiBiT-tag-dependent Luciferase Activity Measurement. Bioprotocol.2023 13(6) e4640. DOI: 10.21769/BioProtoc.4640
Miura, S., Ishida, K., Tanaka, K., Morita, E. Hashimoto, M. Integrasone derivatives isolated from Lepteutypa sp. KT4162 and their anti-HIV-1 integrase activity. J Nat Prod. 2023 86, 4, 1019–1024 DOI: 10.1021/acs.jnatprod.3c00065
Arakawa, M., Yoshida, A., Okamura, S., Ebina, H., Morita, E. A highly sensitive NanoLuc-based protease biosensor for detecting apoptosis and SARS-CoV-2 infection. Sci Rep. 2023 13(1)1753. Doi: 10.1038/s41598-023-28984-4
Ishida, K., Noguchi, T., Kimura, S., Suzuki, H., Ebina, H., Morita E. Tracking of human parvovirus B19 virus-like particles using short peptide tags reveals a membrane-associated extracellular release of these particles. J Virol. 2023 e0163122. Doi: 10.1128/jvi.01631-22
Morita, E. ESCRT-mediated plasma membrane shaping. Plasma Membrane Shaping 1st Edition, Academic Press, 2022 Chapter 7 p91- 103 eBook ISBN 9780323899192, Paper Book ISBN 9780323899116 doi: 10.1016/B978-0-323-89911-6.00003-0
Suzuki, H., Noguchi, T., Matsugu, N., Suzuki, A., Kimura, S., Onishi, M., Kosaka, M., Miyazato, P., Morita, E., Ebina, H. Safety and immunogenicity of parvovirus B19 virus-like particle vaccine lacking phospholipase A2 activity. 2022 40(42):6100-6106. doi: 10.1016/j.vaccine.2022.09.009.
Liu, CC., Liu, YY., Zhou, JF., Chen, X., Chen, H., Hu, JH., Chen, J., Zhang, J., Sun, RC., Wei, JC., Go, YY., Morita, E., Zhou, B. Cellular ESCRT components are recruited to regulate the endocytic trafficking and RNA replication compartment assembly during classical swine fever virus infection. PLoS Pathog. 2022, 18(2):e1010294. doi: 10.1371/journal.ppat. 1010294.
Arakawa, M., Tabata, K., Ishida, K., Kobayashi, M., Arai, A., Ishikawa, T., Suzuki, R., Takeuchi, H., Tripathi, LP., Mizuguchi, K., Morita, E.. Flavivirus recruits the valosin-containing protein (VCP)/NPL4 complex to induce stress granule disassembly for efficient viral genome replication. J Biol Chem. 2022 298(3):101597, doi: 10.1016/j.jbc.2022.101597.
Okudera, M., Odawara, M., Arakawa, M., Kawaguchi, S., Seya, K., Matsumiya, T., Sato, R., Ding, J.,Morita, E.. , Imaizumi, T. Expression of Zinc-finger antiviral protein in hCMEC/D3 human cerebral microvascular endothelial cells: effect of a Toll-like receptor 3 agonist. Neuroimmunomodulation 2021 Dec 22:1-10. doi: 10.1159/000521012.
Suzuki, H., Noguchi, T., Ogawa, K., Miyazato, P., Hatakeyama, Y., Morita, E.. , Ebina, H. Fusion of parvovirus B19 receptor-binding domain and pneumococcal surface protein A induces protective immunity against parvovirus B19 and Streptococcus pneumoniae. Vaccine 2021, 39(36):5146-5152. doi: 10.1016/j.vaccine.2021.07.046.
Morita, E. , Suzuki, Y. Membrane-Associated Flavivirus Replication Complex—Its Organization and Regulation. Viruses 2021, 13(6), 1060 doi: 10.3390/v13061060
Kimura, S., Maeda, K., Nagashima, R., Miura, K., Ebina, H., Tanaka, N., Morita, E. Efficient immunogenic peptide antigen delivery to dendritic cells using an ESCRT-mediated extracellular vesicle formation method. Vaccine 2021, 39(22), 2976-2982. doi: 10.1128/JVI.02234-20.
Tabata, K., Arakawa, M., Ishida, K., Kobayashi, M., Nara, A., Sugimoto, T., Okada, T., Mori K., Morita, E. Endoplasmic reticulum-associated degradation controls virus protein homeostasis that is required for the flavivirus propagation. J Virol. 2021 May 12:JVI.02234-20. doi: 10.1016/j.vaccine.2021.04.021.
Ozaki, R., Ishida, K., Morita, E. , Hanada, Y. Nanoparticle deposition of fluoropolymer CYTOP via holographic femtosecond laser processing and its biochip application. Applied Sciences. 2020, 10(20), 7243
Goto, S., Ishida, K., Suzuki, R., Morita, E. . Split nano luciferase-based assay to measure assembly of Japanese encephalitis virus. Bioprotocol. 2020 May 5, 10:9 e3606.
Tayone, WC., Ishida, K., Goto, S., Tayone, JC., Arakawa, M., Morita, E. , and Hashimoto, M. Anti-Japanese Encephalitis Virus (JEV) Activity of Triterpenes and Flavonoids from Euphorbia hirta. Philippine Journal of Science. 2020 149 (3): 603-613
Arakawa, M., Morita, E. Zika virus infection and replication organelle biogenesis. Elsevier “Zika Virus Biology, Pathology and Control” 2020 in press.
Ishida, K., Goto, S., Ishimura, M., Amanuma, M., Hara, Y., Suzuki, R., Katoh, K., Morita, E. Functional correlation between subcellular localizations of Japanese encephalitis virus capsid protein and virus production. J Virol. 2019 Jul 17. pii: JVI.00612-19.
Arakawa, M., Morita, E. Flavivirus replication organelle biogenesis in the endoplasmic reticulum: comparison with other single-stranded positive-sense RNA viruses. Int J Mol Sci. 2019 20:2336
Morita, E. Membrane closure in stress induced-autophagosome formation. Cell Stress. 2018 2(6):122-124
Tripathi, L.P., Chen, Y. A., Mizuguchi, K andMorita, E. Network-based analysis of host-pathogen interactions. Encyclopedia of Bioinformatics and Computational Biology. 2019 3:932-937
Tabata, K., Nara, A., Omori, H.,Morita, E. Immuno-localization of ESCRT proteins in virus-infected cells by fluorescence and electron microscopy. Methods in Molecular Biology. 2019 1998:73-92.
Tabata, K., Arimoto, M., Arakawa, M., Nara, A., Saito, K., Omori, H., Arai, A., Ishikawa, T., Konishi, E., Suzuki, R., Matsuura, Y., Morita, E. Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum. Cell Rep. 2016 16(9):2339-2347
Hao, F., Itoh, T., Morita, E., Shirahama-Noda, K., Yoshimori, T., Noda, T. The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity. FEBS Lett. 2016 590(1):161-173.
Suzuki, H., Tabata, K., Morita, E., Kawasaki, M., Kato, R., Dobson, RJ., Yoshimori, T., Wakatsuki, S. Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism. Structure. 2014 22(1):47-58.
Fujita, N.†, Morita, E. †, Itoh, T., Tanaka, A., Nakaoka, M., Osada, Y., Umemoto, T., Saitoh, T., Nakatogawa, H., Kobayashi, S., Haraguchi, T., Guan, J.L., Iwai, K., Tokunaga, F., Saito, K., Ishibashi, K., Akira, S., Fukuda, M., Noda, T., Yoshimori, T. Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J Cell Biol. 2013 203(1):115-28 †These authors contributed equally
Tripathi, L.P., Kambara, H., Chen, Y.A., Nishimura, Y., Moriishi, K., Okamoto, T., Morita, E., Abe, T., Mori, Y., Matsuura, Y., Mizuguchi, K. Understanding the biological context of NS5A-host interactions in HCV infection: a network-based approach. J Proteome Res. 2013 Jun 7;12(6):2537-51.
Katoh, H., Okamoto, T., Fukuhara, T., Kambara, H., Morita, E., Mori, Y., Kamitani, W., Matsuura, Y. Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation. J Virol. 2013 Jan;87(1):489-502.
Morita, E., Arii J, Christensen D, Votteler J, Sundquist WI. Attenuated protein expression vectors for use in siRNA rescue experiments. Biotechniques. 2012 Aug;0(0):1-5.
Tripathi LP, Kambara H, Moriishi K, Morita E, Abe T, Mori Y, Chen YA, Matsuura Y, Mizuguchi K. Proteomic analysis of hepatitis C virus (HCV) core protein transfection and host regulator PA28γ knockout in HCV pathogenesis: a network-based study. J Proteome Res. 2012 Jul 6;11(7):3664-79.
Fukuhara T, Kambara H, Shiokawa M, Ono C, Katoh H,Morita, E., Okuzaki D, Maehara Y, Koike K, Matsuura Y. Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus. J Virol. 22012 Aug;86(15):7918-33.
Morita, E., Yoshimori, T. Membrane recruitment of LC3 proteins during autophagosome formation. Hepatol Res. 2012 May;42(5):435-41.
Morita, E. ESCRT Connections: Factor Requirements for Multivesicular Body Formation, Virus Budding and Cell Division. FEBS J. 2012 Apr;279(8):1399-406
Katoh, H., Mori, Y., Kambara, H., Abe, T., Fukuhara, T., Morita, E., Moriishi, K., Kamitani, W., Matsuura, Y. Heterogeneous nuclear ribonucleoprotein A2 participates in the replication of Japanese encephalitis virus through an interaction with viral proteins and RNA. J Virol. 2011 85(21):10976-88
Morita, E., Sandrin, V., McCullough, J., Katsuyama, A., Hamilton, IB., Sundquist, WI. ESCRT-III protein requirements for HIV-1 budding. Cell Host Microbe. 2011, 3:235-42.
Matsunaga, K., Morita, E., Saitoh, T., Akira, S., Ktistakis, NT., Izumi, T., Noda, T., Yoshimori, T. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol. 2010 190(4):511-21.
Morita, E., Colf, LA., Karren, MA., Sandrin, V., Rodesch, CK., Sundquist, WI. Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance. Proc Natl Acad Sci U S A. 2010 107(29):12889-94.
Bajorek, M., Morita, E., Skalicky, JJ, Morham, SG., Babst, M., Sundquist, WI. Biochemical analyses of human IST1 and its function in cytokinesis. Mol Biol Cell 2009 20(5):1360-73.
Kieffer, C., Skalicky JJ., Morita, E., De Domenico, I., Ward, DM., Kaplan, J., Sundquist, WI. A New Functionally Important ESCRT-III Recognition Mode for the VPS4 ATPases. Dev. Cell 2008, 15(1):62-73.
Chung, HY., Morita, E., von Schwedler, U., Müller, B., Kräusslich, HG. and Sundquist, WI.. NEDD4L Overexpression Rescues Release and Infectivity of HIV-1 Constructs Lacking PTAP and YPXL Late Domains. J Virol. 2008, 82(10):4884-97.
Morita, E., Sandrin, V., Chung, HY., Morham, SG., Gygi, SP., Rodesch, CK. and Sundquist,, WI. Human ESCRT and ALIX Proteins Interact with Proteins of the Midbody and Function in Cytokinesis. EMBO J, 2007, 26(19):4215-27.
Morita, E., Sandrin, V., Alam, SL., Eckert, DM., Gygi, SP., Sundquist, WI. Identification of MVB12 Proteins as Human ESCRT-I Subunits that Function in HIV Budding. Cell Host Microbe 2007, 2(1):19-28
Morita, E., Sundquist, WI. Retrovirus budding. Annu Rev Cell Dev Biol. 2004 20:395-425.
Nakashima, A., Morita, E., Saito, S., Sugamura, K. Human Parvovirus B19 nonstructural protein transactivates the p21/WAF1 through Sp1. Virology 2004 329:493-504.
von Schwedler, UK., Stuchell, M., Muller, B., Ward, DM., Chung, HY., Morita, E., Wang, HE., Davis, T., He, GP., Cimbora, DM., Scott, A., Krausslich, HG., Kaplan, J., Morham, SG., Sundquist, WI. The protein network of HIV budding. Cell. 2003 114:701-13.
Kanazawa, C., Morita, E., Yamada, M., Ishii, N., Miura, S., Asao, H., Yoshimori, T., Sugamura, K. Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation. Biochem Biophys Res Commun. 2003 309:848-56.
Morita, E., Nakashima, A., Asao, H., Sato, H., Sugamura, K. Human parvovirus B19 nonstructural protein (NS1) induces cell cycle arrest at G(1) phase. J Virol. 2003 77:2915-21.
Morita, E., Sugamura, K. Human parvovirus B19-induced cell cycle arrest and apoptosis. Springer Semin Immunopathol 2002 24:187-199.
Chisaka, H., Morita, E., Murata, K., Ishii, N., Yaegashi, N., Sugamura, K. A transgenic mouse model for nonimmune hydrops fetalis induced by the NS1 gene of human parvovirus B19. J Gen Virol. 2002 83:273-81.
Morita, E., Tada, K., Chisaka, H., Asao, H., Sato, H., Yaegashi, N., Sugamura, K. Human parvovirus B19 induces cell cycle arrest at G(2) phase with accumulation of mitotic cyclins. J Virol. 2001 75:7555-63.
Kasai, H., Morita, E., Hatakeyama, K., Sugiyama K. Characterization of haemagglutinin -esterase protein (HE) of murine corona virus DVIM by monoclonal antibodies. Arch Virol. 1998;143:1941-8.
Morita, E., Ebina, H., Muto, A., Himeno, H., Hatakeyama, K., Sugiyama, K. Primary structures of hemagglutinin-esterase and spike glycoproteins of murine coronavirus DVIM. Virus Genes 1998;17:123-8.